ABSTRACT
An outbreak of coronavirus pneumonia was firstly documented in Wuhan, Hubei Province, China (December 2019), with an indication of human-to-human transmission. The causative agent identified for coronavirus disease 2019 (COVID-19) is the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). America, Italy, India, and Africa became new venues of COVID infection;the overall data of patients and death is increasing day by day. Generally inplace of most of the infected people develop respiratory symptoms (throat pain, cough, etc.), fever, and chest opacity on CT scan and X-ray. A few numbers of suspected persons are found asymptomatic;they may serve as carriers for infection. As a point of care, the patient diagnosis is compulsory, and only the diagnosis can provide a real-time condition of patients and can be helpful in arresting the spreading of the infection. In the present chapter, we focused on illustrating various diagnostic techniques that have been employed by the world for the detection of the coronavirus. The diagnostic techniques are categorized into molecular and serologic assay techniques. The nucleic acid is detected in molecular assay, whereas the serologic assay uses antigen-antibody reaction. © Springer Nature Switzerland AG 2021.